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Evaluation of carbon:nitrogen ratio in semi-defined culture medium to tacrolimus biosynthesis by Streptomyces tsukubaensis and the effect on bacterial growth

Tacrolimus is an immunosuppressant produced by several Streptomyces species, widely used in transplantolgy and dermatology. In this report, attempts have been made to enhance tacrolimus productivity by altering the primary carbon source on culture media. In order to better understand the effects of...

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Bibliografische gegevens
Gepubliceerd in:Biotechnol Rep (Amst)
Hoofdauteurs: Moreira, Jean Vinícius, Silva, Seforah Carolina Marques, Cremasco, Marco Aurélio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068638/
https://ncbi.nlm.nih.gov/pubmed/32190550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2020.e00440
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