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Evaluation of carbon:nitrogen ratio in semi-defined culture medium to tacrolimus biosynthesis by Streptomyces tsukubaensis and the effect on bacterial growth

Tacrolimus is an immunosuppressant produced by several Streptomyces species, widely used in transplantolgy and dermatology. In this report, attempts have been made to enhance tacrolimus productivity by altering the primary carbon source on culture media. In order to better understand the effects of...

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Detalhes bibliográficos
Publicado no:Biotechnol Rep (Amst)
Main Authors: Moreira, Jean Vinícius, Silva, Seforah Carolina Marques, Cremasco, Marco Aurélio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068638/
https://ncbi.nlm.nih.gov/pubmed/32190550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2020.e00440
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