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Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior

The nucleus accumbens (NAc) plays a key role in drug-related behavior and natural reward learning. Synaptic plasticity in dopamine D1 and D2 receptor medium spiny neurons (MSNs) of the NAc and the endogenous cannabinoid (eCB) system have been implicated in reward seeking. However, the precise molecu...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Bilbao, Ainhoa, Neuhofer, Daniela, Sepers, Marja, Wei, Shou-peng, Eisenhardt, Manuela, Hertle, Sarah, Lassalle, Olivier, Ramos-Uriarte, Almudena, Puente, Nagore, Lerner, Raissa, Grandes, Pedro, Lutz, Beat, Manzoni, Olivier J., Spanagel, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068121/
https://ncbi.nlm.nih.gov/pubmed/32179475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100951
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