Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome

Fragile X syndrome, the most commonly known genetic cause of autism, is due to loss of the fragile X mental retardation protein, which regulates signal transduction at metabotropic glutamate receptor-5 in the brain. Fragile X mental retardation protein deletion in mice enhances metabotropic glutamat...

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Hlavní autoři: Jung, Kwang-Mook, Sepers, Marja, Henstridge, Christopher M., Lassalle, Olivier, Neuhofer, Daniela, Martin, Henry, Ginger, Melanie, Frick, Andreas, DiPatrizio, Nicholas V., Mackie, Ken, Katona, Istvan, Piomelli, Daniele, Manzoni, Olivier J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657999/
https://ncbi.nlm.nih.gov/pubmed/23011134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2045
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