Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

Immune checkpoint blockade (ICB)-based or natural cancer immune responses largely eliminate tumours. Yet, they require additional mechanisms to arrest those cancer cells that are not rejected. Cytokine-induced senescence (CIS) can stably arrest cancer cells, suggesting that interferon-dependent indu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Brenner, Ellen, Schörg, Barbara F., Ahmetlić, Fatima, Wieder, Thomas, Hilke, Franz Joachim, Simon, Nadine, Schroeder, Christopher, Demidov, German, Riedel, Tanja, Fehrenbacher, Birgit, Schaller, Martin, Forschner, Andrea, Eigentler, Thomas, Niessner, Heike, Sinnberg, Tobias, Böhm, Katharina S., Hömberg, Nadine, Braumüller, Heidi, Dauch, Daniel, Zwirner, Stefan, Zender, Lars, Sonanini, Dominik, Geishauser, Albert, Bauer, Jürgen, Eichner, Martin, Jarick, Katja J., Beilhack, Andreas, Biskup, Saskia, Döcker, Dennis, Schadendorf, Dirk, Quintanilla-Martinez, Leticia, Pichler, Bernd J., Kneilling, Manfred, Mocikat, Ralph, Röcken, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067802/
https://ncbi.nlm.nih.gov/pubmed/32165639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14987-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker