Ablation of IL-17A leads to severe colitis in IL-10-deficient mice: implications of myeloid-derived suppressor cells and NO production

IL-10 is an immune regulatory cytokine and its genetic defect leads to gastrointestinal inflammation in humans and mice. Moreover, the IL-23/T(h)17 axis is known to be involved in these inflammatory disorders. IL-17A, a representative cytokine produced by T(h)17 cells, has an important role for the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Tachibana, Masashi, Watanabe, Nobumasa, Koda, Yuzo, Oya, Yukako, Kaminuma, Osamu, Katayama, Kazufumi, Fan, Zifei, Sakurai, Fuminori, Kawabata, Kenji, Hiroi, Takachika, Mizuguchi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067553/
https://ncbi.nlm.nih.gov/pubmed/31755523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxz076
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados