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Direct coupling analysis of epistasis in allosteric materials
In allosteric proteins, the binding of a ligand modifies function at a distant active site. Such allosteric pathways can be used as target for drug design, generating considerable interest in inferring them from sequence alignment data. Currently, different methods lead to conflicting results, in pa...
में बचाया:
| में प्रकाशित: | PLoS Comput Biol |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7067494/ https://ncbi.nlm.nih.gov/pubmed/32119660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007630 |
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