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Contribution of hexose-6-phosphate dehydrogenase to NADPH content and redox environment in the endoplasmic reticulum

Background: Hexose-6-phosphate dehydrogenase (H6PD) has been considered to be a main source of NADPH in the endoplasmic reticulum. It provides reducing equivalents to 11-hydroxysteroid dehydrogenase type 1 for in situ re-activation of glucocorticoids. H6PD null mice indeed show signs of glucocortico...

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Detalhes bibliográficos
Publicado no:Redox Rep
Main Authors: Rogoff, Daniela, Black, Kelli, McMillan, D. Randy, White, Perrin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067336/
https://ncbi.nlm.nih.gov/pubmed/20500987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/174329210X12650506623249
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