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Nucleolus as an oxidative stress sensor in the yeast Saccharomyces cerevisiae

In mammals, the nucleolus is thought to be a stress sensor; upon cellular stress conditions, a release of nucleolar proteins and down-regulation of rDNA transcription occurs. Since yeast Rrn3p is a homolog of the mammalian RNA polymerase I (Pol I)-specific transcription factor TIF-IA, we decided to...

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Détails bibliographiques
Publié dans:Redox Rep
Auteurs principaux: Lewinska, Anna, Wnuk, Maciej, Grzelak, Agnieszka, Bartosz, Grzegorz
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067331/
https://ncbi.nlm.nih.gov/pubmed/20500990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/174329210X12650506623366
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