Rare Genetic Variants Associated with Sudden Cardiac Death in Adults

BACKGROUND: Sudden cardiac death occurs in ~220,000 U.S. adults annually, the majority of whom have no prior symptoms or cardiovascular diagnosis. Rare pathogenic DNA variants in any of 49 genes can predispose to four important causes of sudden cardiac death – cardiomyopathy, coronary artery disease...

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Udgivet i:J Am Coll Cardiol
Main Authors: Khera, Amit V., Mason-Suares, Heather, Brockman, Deanna, Wang, Minxian, VanDenburgh, Martin J., Senol-Cosar, Ozlem, Patterson, Candace, Newton-Cheh, Christopher, Zekavat, Seyedeh M., Pester, Julie, Chasman, Daniel I., Kabrhel, Christopher, Jensen, Majken K., Manson, JoAnn E., Gaziano, J. Michael, Taylor, Kent D., Sotoodehnia, Nona, Post, Wendy S., Rich, Stephen S., Rotter, Jerome I., Lander, Eric S., Rehm, Heidi L., Ng, Kenney, Philippakis, Anthony, Lebo, Matthew, Albert, Christine M., Kathiresan, Sekar
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067308/
https://ncbi.nlm.nih.gov/pubmed/31727422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.08.1060
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