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SOCS1 blocks G1-S transition in hepatocellular carcinoma by reducing the stability of the CyclinD1/CDK4 complex in the nucleus

Inhibitors of the CDK family of proteins have been approved for the treatment of a variety of tumours; however, the development of new drugs administered in combination with CDK inhibitors is expected to improve the therapeutic effect. We identified the function of suppressor of cytokine signalling...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Aging (Albany NY)
Κύριοι συγγραφείς: Ding, Jun, Xu, Kangdi, Sun, Suwan, Qian, Chao, Yin, Shengyong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen, Zhang, Wei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066915/
https://ncbi.nlm.nih.gov/pubmed/32096766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102865
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