Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing

Escherichia coli cells respond to a period of famine by globally reorganizing their gene expression. The changes are known as the stringent response, which is orchestrated by the alarmone ppGpp that binds directly to RNA polymerase. The resulting changes in gene expression are particularly well stud...

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Detalles Bibliográficos
Publicado en:Front Genet
Autores principales: Gummesson, Bertil, Shah, Shiraz Ali, Borum, Alexander Skov, Fessler, Mathias, Mitarai, Namiko, Sørensen, Michael Askvad, Svenningsen, Sine Lo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066862/
https://ncbi.nlm.nih.gov/pubmed/32211022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00144
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