Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing

Escherichia coli cells respond to a period of famine by globally reorganizing their gene expression. The changes are known as the stringent response, which is orchestrated by the alarmone ppGpp that binds directly to RNA polymerase. The resulting changes in gene expression are particularly well stud...

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Bibliographic Details
Published in:Front Genet
Main Authors: Gummesson, Bertil, Shah, Shiraz Ali, Borum, Alexander Skov, Fessler, Mathias, Mitarai, Namiko, Sørensen, Michael Askvad, Svenningsen, Sine Lo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066862/
https://ncbi.nlm.nih.gov/pubmed/32211022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00144
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