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IDO Targeting in Sarcoma: Biological and Clinical Implications
Sarcomas are heterogeneous malignant mesenchymal neoplasms with limited sensitivity to immunotherapy. We recently demonstrated an increase in Kynurenine Pathway (KP) activity in the plasma of sarcoma patients treated with pembrolizumab. While the KP has already been described to favor immune escape...
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| Publicat a: | Front Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066301/ https://ncbi.nlm.nih.gov/pubmed/32194552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00274 |
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