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Delivery across the blood-brain barrier: nanomedicine for glioblastoma multiforme

The malignant brain cancer, glioblastoma multiforme (GBM), is heterogeneous, infiltrative, and associated with chemo- and radioresistance. Despite pharmacological advances, prognosis is poor. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conv...

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Detalles Bibliográficos
Publicado en:Drug Deliv Transl Res
Main Authors: Jena, Lynn, McErlean, Emma, McCarthy, Helen
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066289/
https://ncbi.nlm.nih.gov/pubmed/31728942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-019-00679-2
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