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An improved method for culturing myotubes on laminins for the robust clustering of postsynaptic machinery
Motor neurons form specialized synapses with skeletal muscle fibers, called neuromuscular junctions (NMJs). Cultured myotubes are used as a simplified in vitro system to study the postsynaptic specialization of muscles. The stimulation of myotubes with the glycoprotein agrin or laminin-111 induces t...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066178/ https://ncbi.nlm.nih.gov/pubmed/32161296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61347-x |
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