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Perplexing Role of P-Glycoprotein in Tumor Microenvironment

Development of multidrug resistance (MDR) still remains a major obstacle to the long-term success of cancer therapy. P-glycoprotein (P-gp) is a well-identified membrane transporter with capability to efflux drug molecules out of the cancer cell leading to reduced efficiency of chemotherapy. Cancer c...

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Publicat a:Front Oncol
Autors principals: Robinson, Kianna, Tiriveedhi, Venkataswarup
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066112/
https://ncbi.nlm.nih.gov/pubmed/32195185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00265
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