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P-glycoprotein-targeted photodynamic therapy boosts cancer nanomedicine by priming tumor microenvironment

Cancer nanomedicines only modestly improve the overall survival of patients because their anticancer activity is limited by biological barriers posed by the tumor microenvironment. Currently, all the drugs in FDA-approved cancer nanomedicines are substrates for P-glycoprotein (Pgp), and thus, Pgp-me...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Mao, Chengqiong, Li, Fang, Zhao, Yan, Debinski, Waldemar, Ming, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299702/
https://ncbi.nlm.nih.gov/pubmed/30613297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29580
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