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Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine

INTRODUCTION: Duchenne muscular dystrophy (DMD) is an X-linked handicapping disease due to the loss of an essential muscle protein dystrophin. Dystrophin-null animals have been extensively used to study disease mechanisms and to develop experimental therapeutics. Despite decades of research, however...

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Pubblicato in:Expert Opin Drug Discov
Autori principali: Wasala, Nalinda B., Chen, Shi-jie, Duan, Dongsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065965/
https://ncbi.nlm.nih.gov/pubmed/32000537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2020.1718100
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