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E3 ubiquitin ligase Fbw7 regulates the survival of mature B cells
Mature naïve B cells expressing B cell receptors (BCRs) of the IgM and IgD isotypes respond to antigen in secondary lymphoid organs. However, the vast majority of B cells do not undergo productive antigen encounter, and have finite life spans dependent on survival signals propagated by the BCR and t...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7065954/ https://ncbi.nlm.nih.gov/pubmed/32005754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901156 |
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