Combined loss of ghrelin receptor and cannabinoid CB1 receptor in mice decreases survival but does not additively reduce body weight or eating

Ghrelin administration increases food intake, body weight (BW), adiposity, and blood glucose. In contrast, although mouse models lacking ghrelin or its receptor (GHSR) exhibit life-threatening hypoglycemia in starvation-like states, they do not exhibit appreciable reductions in food intake, BW, adip...

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Gepubliceerd in:Neuroscience
Hoofdauteurs: Mani, Bharath K., Castorena, Carlos M., Vianna, Claudia R., Lee, Charlotte E., Metzger, Nathan P., Vijayaraghavan, Prasanna, Osborne-Lawrence, Sherri, Elmquist, Joel K., Zigman, Jeffrey M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065928/
https://ncbi.nlm.nih.gov/pubmed/31520709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.09.005
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