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β(1)-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals

Ghrelin is an orexigenic gastric peptide hormone secreted when caloric intake is limited. Ghrelin also regulates blood glucose, as emphasized by the hypoglycemia that is induced by caloric restriction in mouse models of deficient ghrelin signaling. Here, we hypothesized that activation of β(1)-adren...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Mani, Bharath K., Osborne-Lawrence, Sherri, Vijayaraghavan, Prasanna, Hepler, Chelsea, Zigman, Jeffrey M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004971/
https://ncbi.nlm.nih.gov/pubmed/27548523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86270
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