β(1)-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals

Ghrelin is an orexigenic gastric peptide hormone secreted when caloric intake is limited. Ghrelin also regulates blood glucose, as emphasized by the hypoglycemia that is induced by caloric restriction in mouse models of deficient ghrelin signaling. Here, we hypothesized that activation of β(1)-adren...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Mani, Bharath K., Osborne-Lawrence, Sherri, Vijayaraghavan, Prasanna, Hepler, Chelsea, Zigman, Jeffrey M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004971/
https://ncbi.nlm.nih.gov/pubmed/27548523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86270
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