Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight

Expressed in the small intestine, retinol-binding protein 2 (RBP2) facilitates dietary retinoid absorption. Rbp2-deficient (Rbp2(−/−)) mice fed a chow diet exhibit by 6-7 months-of-age higher body weights, impaired glucose metabolism, and greater hepatic triglyceride levels compared to controls. The...

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Publicado no:Sci Adv
Main Authors: Lee, Seung-Ah, Yang, Kryscilla Jian Zhang, Brun, Pierre-Jacques, Silvaroli, Josie A., Yuen, Jason J., Shmarakov, Igor, Jiang, Hongfeng, Feranil, Jun B., Li, Xueting, Lackey, Atreju I., Krężel, Wojciech, Leibel, Rudolph L., Libien, Jenny, Storch, Judith, Golczak, Marcin, Blaner, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065888/
https://ncbi.nlm.nih.gov/pubmed/32195347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8937
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