Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight

Expressed in the small intestine, retinol-binding protein 2 (RBP2) facilitates dietary retinoid absorption. Rbp2-deficient (Rbp2(−/−)) mice fed a chow diet exhibit by 6-7 months-of-age higher body weights, impaired glucose metabolism, and greater hepatic triglyceride levels compared to controls. The...

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Publicado en:Sci Adv
Autores principales: Lee, Seung-Ah, Yang, Kryscilla Jian Zhang, Brun, Pierre-Jacques, Silvaroli, Josie A., Yuen, Jason J., Shmarakov, Igor, Jiang, Hongfeng, Feranil, Jun B., Li, Xueting, Lackey, Atreju I., Krężel, Wojciech, Leibel, Rudolph L., Libien, Jenny, Storch, Judith, Golczak, Marcin, Blaner, William S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065888/
https://ncbi.nlm.nih.gov/pubmed/32195347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8937
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