Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight

Expressed in the small intestine, retinol-binding protein 2 (RBP2) facilitates dietary retinoid absorption. Rbp2-deficient (Rbp2(−/−)) mice fed a chow diet exhibit by 6-7 months-of-age higher body weights, impaired glucose metabolism, and greater hepatic triglyceride levels compared to controls. The...

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Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Lee, Seung-Ah, Yang, Kryscilla Jian Zhang, Brun, Pierre-Jacques, Silvaroli, Josie A., Yuen, Jason J., Shmarakov, Igor, Jiang, Hongfeng, Feranil, Jun B., Li, Xueting, Lackey, Atreju I., Krężel, Wojciech, Leibel, Rudolph L., Libien, Jenny, Storch, Judith, Golczak, Marcin, Blaner, William S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065888/
https://ncbi.nlm.nih.gov/pubmed/32195347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8937
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