Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons

Several barriers protect the central nervous system (CNS) from pathogen invasion. Yet viral infections of the CNS are common and often debilitating. Understanding how neurotropic viruses co-opt host machinery to overcome challenges to neuronal entry and transmission is important to combat these infe...

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Pubblicato in:PLoS Pathog
Autori principali: Aravamudhan, Pavithra, Raghunathan, Krishnan, Konopka-Anstadt, Jennifer, Pathak, Amrita, Sutherland, Danica M., Carter, Bruce D., Dermody, Terence S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065821/
https://ncbi.nlm.nih.gov/pubmed/32109948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008380
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