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Copanlisib synergizes with conventional and targeted agents including venetoclax in B- and T-cell lymphoma models
Copanlisib is a pan–class I phosphoinositide 3-kinase (PI3K) inhibitor with preferred activity toward PI3Kα and PI3Kδ. Despite the clear overall clinical benefit, the number of patients achieving complete remissions with the single agent is relatively low, a problem shared by the vast majority of ta...
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| Veröffentlicht in: | Blood Adv |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7065481/ https://ncbi.nlm.nih.gov/pubmed/32126142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000844 |
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