Frequency of circulating CD8+CD73+T cells is associated with survival in nivolumab-treated melanoma patients

BACKGROUND: PD-1 blocking agents, such as nivolumab, have demonstrated clear anti-tumor effects and clinical benefits in a subset of patients with advanced malignancies. Nonetheless, more efforts are needed to identify reliable biomarkers for outcome, to correctly select patients who will benefit fr...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Capone, Mariaelena, Fratangelo, Federica, Giannarelli, Diana, Sorrentino, Claudia, Turiello, Roberta, Zanotta, Serena, Galati, Domenico, Madonna, Gabriele, Tuffanelli, Marilena, Scarpato, Luigi, Grimaldi, Antonio M., Esposito, Assunta, Azzaro, Rosa, Pinto, Antonio, Cavalcanti, Ernesta, Pinto, Aldo, Morello, Silvana, Ascierto, Paolo A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065327/
https://ncbi.nlm.nih.gov/pubmed/32160899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02285-0
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