Whole‐exome sequencing of ovarian cancer families uncovers putative predisposition genes

Despite the identification of several ovarian cancer (OC) predisposition genes, a large proportion of familial OC risk remains unexplained. We adopted a two‐stage design to identify new OC predisposition genes. We first carried out a large germline whole‐exome sequencing study on 158 patients from 1...

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Dades bibliogràfiques
Publicat a:Int J Cancer
Autors principals: Zhu, Qianqian, Zhang, Jianmin, Chen, Yanmin, Hu, Qiang, Shen, He, Huang, Ruea‐Yea, Liu, Qian, Kaur, Jasmine, Long, Mark, Battaglia, Sebastiano, Eng, Kevin H., Lele, Shashikant B., Zsiros, Emese, Villella, Jeannine, Lugade, Amit, Yao, Song, Liu, Song, Moysich, Kirsten, Odunsi, Kunle O.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Cancer Epidemiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065147/
https://ncbi.nlm.nih.gov/pubmed/31265121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32545
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