NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor

N‐methyl‐d‐aspartate receptors (NMDARs) mediate both physiological and pathophysiological processes, although selective ligands lack broad clinical utility. NMDARs are composed of multiple subunits, but N‐methyl‐d‐aspartate receptor subunit 2 (GluN2) is predominately responsible for functional heter...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Bowers, M. Scott, Cacheaux, Luisa P., Sahu, Srishti U., Schmidt, Mary E., Sennello, Joseph A., Leaderbrand, Katherine, Khan, M. Amin, Kroes, Roger A., Moskal, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065110/
https://ncbi.nlm.nih.gov/pubmed/31376158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14845
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