NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor

N‐methyl‐d‐aspartate receptors (NMDARs) mediate both physiological and pathophysiological processes, although selective ligands lack broad clinical utility. NMDARs are composed of multiple subunits, but N‐methyl‐d‐aspartate receptor subunit 2 (GluN2) is predominately responsible for functional heter...

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Publicat a:J Neurochem
Autors principals: Bowers, M. Scott, Cacheaux, Luisa P., Sahu, Srishti U., Schmidt, Mary E., Sennello, Joseph A., Leaderbrand, Katherine, Khan, M. Amin, Kroes, Roger A., Moskal, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
ORIGINAL ARTICLES
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065110/
https://ncbi.nlm.nih.gov/pubmed/31376158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14845
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