Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signaling

In this study, we examined the Ca(2+)‐permeable Piezo1 channel, a newly identified mechanosensing ion channel, in human dental pulp‐derived mesenchymal stem cells (MSCs) and hypothesized that activation of the Piezo1 channel regulates MSC migration via inducing ATP release and activation of the P2 r...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Mousawi, Fatema, Peng, Hongsen, Li, Jing, Ponnambalam, Sreenivasan, Roger, Sébastien, Zhao, Hucheng, Yang, Xuebin, Jiang, Lin‐Hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Tissue‐specific Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064961/
https://ncbi.nlm.nih.gov/pubmed/31746084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3114
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