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Peptide‐Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

Protein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell‐ and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 diabetes. So far, however, only one of the numerous anti‐amyloid molecules has reached patients. This Minirev...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Armiento, Valentina, Spanopoulou, Anna, Kapurniotu, Aphrodite
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064928/
https://ncbi.nlm.nih.gov/pubmed/31529602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906908
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