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Peptide‐Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

Protein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell‐ and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 diabetes. So far, however, only one of the numerous anti‐amyloid molecules has reached patients. This Minirev...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Armiento, Valentina, Spanopoulou, Anna, Kapurniotu, Aphrodite
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064928/
https://ncbi.nlm.nih.gov/pubmed/31529602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906908
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