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Protein Misfolding and Aggregation in Ageing and Disease: Molecular Processes and Therapeutic Perspectives

Although intensively researched, the fundamental mechanism of protein misfolding that leads to protein aggregation and associated diseases remains somewhat enigmatic. The failure of a protein to correctly fold de novo or to remain correctly folded can have profound consequences on a living system es...

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Detalhes bibliográficos
Main Authors: Tuite, Mick F, Melki, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634451/
https://ncbi.nlm.nih.gov/pubmed/19164925
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