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Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts

Tertiary lymphoid structures (TLS) accumulate at sites of chronic injury where they function as an ectopic germinal center, fostering local autoimmune responses. Vascular injury leads to the release of endothelial‐derived apoptotic exosome‐like vesicles (ApoExo) that contribute to rejection in trans...

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Foilsithe in:Am J Transplant
Main Authors: Dieudé, Mélanie, Turgeon, Julie, Karakeussian Rimbaud, Annie, Beillevaire, Déborah, Qi, Shijie, Patey, Nathalie, Gaboury, Louis A., Boilard, Éric, Hébert, Marie‐Josée
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064890/
https://ncbi.nlm.nih.gov/pubmed/31729155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15707
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