Endothelial extracellular vesicle miR-423-5p regulates microvascular homeostasis and renal function after ischemia-reperfusion injury

Microvascular rarefaction substantially contributes to renal dysfunction following ischemia-reperfusion injury (IRI). We characterized the microRNA signature of extracellular vesicles (EVs) released during endothelial apoptosis to identify biomarkers and regulators of microvascular rarefaction and r...

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Bibliografische gegevens

Hoofdauteurs:	Francis Migneault, Hyunyun Kim, Alice Doreille, Shanshan Lan, Alexis Gendron, Marie-Hélène Normand, Annie Karakeussian Rimbaud, Martin Dupont, Isabelle Bourdeau, Éric Bonneil, Julie Turgeon, Sylvie Dussault, Pierre Thibault, Mélanie Dieudé, Éric Boilard, Alain Rivard, Héloïse Cardinal, Marie-Josée Hébert
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical investigation 2025-05-01
Reeks:	JCI Insight
Onderwerpen:	Cell biology Nephrology Vascular biology
Online toegang:	https://doi.org/10.1172/jci.insight.181937
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