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A NOVEL ROLE OF ERK5 IN INTEGRIN-MEDIATED CELL ADHESION AND MOTILITY IN CANCER CELLS VIA FAK SIGNALING

In metastatic cancer, high expression levels of vitronectin (VN) receptors (integrins), FAK, and ERK5 are reported. We hypothesized that integrin-mediated ERK5 activation via FAK may play a pivotal role in cell adhesion, motility, and metastasis. ERK5 and FAK phosphorylation when metastatic MDA-MB-2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Physiol
Egile Nagusiak: Sawhney, Rajinder S., Liu, Wensheng, Brattain, Michael G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064882/
https://ncbi.nlm.nih.gov/pubmed/19089993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21662
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