Nε-Carboxymethyl-Lysine Negatively Regulates Foam Cell Migration via the Vav1/Rac1 Pathway

BACKGROUND: Macrophage-derived foam cells play a central role in atherosclerosis, and their ultimate fate includes apoptosis, promotion of vascular inflammation, or migration to other tissues. Nε-Carboxymethyl-lysine (CML), the key active component of advanced glycation end products, induced foam ce...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Bao, Zhengyang, Zhang, Lili, Li, Lihua, Yan, Jinchuan, Pang, Qiwen, Sun, Zhen, Geng, Yue, Jing, Lele, Shao, Chen, Wang, Zhongqun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064830/
https://ncbi.nlm.nih.gov/pubmed/32190703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1906204
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