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Some Statistical Consideration in Transcriptome-Wide Association Studies

Transcriptome-wide association study (TWAS) has become popular in integrating a reference eQTL dataset with an independent main GWAS dataset to identify (putatively) causal genes, shedding mechanistic insights to biological pathways from genetic variants to a GWAS trait mediated by gene expression....

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Xue, Haoran, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064426/
https://ncbi.nlm.nih.gov/pubmed/31821608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22274
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