Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions

BACKGROUND: Cutaneous lupus erythematosus (CLE) is an interferon (IFN) -driven autoimmune skin disease characterized by an extensive cytotoxic lesional inflammation with activation of different innate immune pathways. Aim of our study was to investigate the specific role of Janus kinase 1 (JAK1) act...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Fetter, Tanja, Smith, Paul, Guel, Tugce, Braegelmann, Christine, Bieber, Thomas, Wenzel, Joerg
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064060/
https://ncbi.nlm.nih.gov/pubmed/32194562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00344
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