Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models

The dominant white phenotype in pigs is thought to be mainly due to a structural mutation in the KIT gene, a splice mutation (G > A) at the first base in intron 17 which leads to the deletion of exon 17 in the mature KIT mRNA. However, this hypothesis has not yet been validated by functional stud...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Sun, Guanjie, Liang, Xinyu, Qin, Ke, Qin, Yufeng, Shi, Xuan, Cong, Peiqing, Mo, Delin, Liu, Xiaohong, Chen, Yaosheng, He, Zuyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063667/
https://ncbi.nlm.nih.gov/pubmed/32194624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00138
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