Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models

The dominant white phenotype in pigs is thought to be mainly due to a structural mutation in the KIT gene, a splice mutation (G > A) at the first base in intron 17 which leads to the deletion of exon 17 in the mature KIT mRNA. However, this hypothesis has not yet been validated by functional stud...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Sun, Guanjie, Liang, Xinyu, Qin, Ke, Qin, Yufeng, Shi, Xuan, Cong, Peiqing, Mo, Delin, Liu, Xiaohong, Chen, Yaosheng, He, Zuyong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063667/
https://ncbi.nlm.nih.gov/pubmed/32194624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00138
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