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Classifying Drugs by their Arrhythmogenic Risk Using Machine Learning

All medications have adverse effects. Among the most serious of these are cardiac arrhythmias. Current paradigms for drug safety evaluation are costly, lengthy, conservative, and impede efficient drug development. Here, we combine multiscale experiment and simulation, high-performance computing, and...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Sahli-Costabal, Francisco, Seo, Kinya, Ashley, Euan, Kuhl, Ellen
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063479/
https://ncbi.nlm.nih.gov/pubmed/32023435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.01.012
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