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Classifying Drugs by their Arrhythmogenic Risk Using Machine Learning

All medications have adverse effects. Among the most serious of these are cardiac arrhythmias. Current paradigms for drug safety evaluation are costly, lengthy, conservative, and impede efficient drug development. Here, we combine multiscale experiment and simulation, high-performance computing, and...

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Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Sahli-Costabal, Francisco, Seo, Kinya, Ashley, Euan, Kuhl, Ellen
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063479/
https://ncbi.nlm.nih.gov/pubmed/32023435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.01.012
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