PET imaging shows no changes in TSPO brain density after IFN-α immune challenge in healthy human volunteers

Depression is associated with peripheral inflammation, but its link with brain microglial activity remains unclear. In seven healthy males, we used repeated translocator protein-Positron Emission Tomography (TSPO-PET) dynamic scans with [(11)C]PBR28 to image brain microglial activation before and 24...

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Détails bibliographiques
Publié dans:Transl Psychiatry
Auteurs principaux: Nettis, M. A., Veronese, M., Nikkheslat, N., Mariani, N., Lombardo, G., Sforzini, L., Enache, D., Harrison, N. A., Turkheimer, F. E., Mondelli, V., Pariante, C. M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063038/
https://ncbi.nlm.nih.gov/pubmed/32152285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-0768-z
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