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Up-Regulation of MiRNA-125a-5p Inhibits Cell Proliferation and Increases EGFR-TKI Induced Apoptosis in Lung Cancer Cells

BACKGROUND: Despite the dramatic efficacy of erlotinib, an EGFR tyrosine kinase inhibitor (TKI), most of non-small cell lung cancer (NSCLC) patients ultimately acquire resistance to this agent. Different studies indicated that miRNA-125a-5p is down-regulated in human lung cancer cells and may functi...

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Pubblicato in:Asian Pac J Cancer Prev
Autori principali: Jamal, Jamal, Molaee, Neda, Karami, Hadi
Natura: Artigo
Lingua:Inglês
Pubblicazione: West Asia Organization for Cancer Prevention 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062986/
https://ncbi.nlm.nih.gov/pubmed/31759360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2019.20.11.3361
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