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Targeting Epidermal Growth Factor Receptor by MiRNA-145 Inhibits Cell Growth and Sensitizes NSCLC Cells to Erlotinib
BACKGROUND: Despite effective activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as erlotinib, all non-small cell lung cancer (NSCLC) patients eventually acquire resistance to these agents. Studies have demonstrated that down-regulation of miRNA-145 leads to...
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| Publicado no: | Asian Pac J Cancer Prev |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
West Asia Organization for Cancer Prevention
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6976848/ https://ncbi.nlm.nih.gov/pubmed/31554377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2019.20.9.2781 |
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