Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease for which the pathophysiological mechanisms of motor neuron loss are not precisely clarified. Environmental and epigenetic mechanisms such as microRNAs (miRNAs) could have a role in disease progression. We studied the expression patt...

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Pubblicato in:Sci Rep
Autori principali: De Luna, Noemi, Turon-Sans, Joana, Cortes-Vicente, Elena, Carrasco-Rozas, Ana, Illán-Gala, Ignacio, Dols-Icardo, Oriol, Clarimón, Jordi, Lleó, Alberto, Gallardo, Eduard, Illa, Isabel, Rojas-García, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062873/
https://ncbi.nlm.nih.gov/pubmed/32152380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61246-1
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