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Effects of Gsta4 Deficiency on Age-related Cochlear Pathology and Hearing Loss in Mice
The glutathione transferase (GST) detoxification system converts exogenous and endogenous toxins into a less toxic form by conjugating the toxic compound to reduced glutathione (GSH) by a variety of GST enzymes. Of the ~20 GST isoforms, GSTA4 exhibits high catalytic efficiency toward 4-hydroxynonena...
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| 出版年: | Exp Gerontol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062562/ https://ncbi.nlm.nih.gov/pubmed/32044382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2020.110872 |
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