Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets

Lung group 2 innate lymphoid cells (ILC2s) drive allergic inflammation and promote tissue repair. ILC2 development is dependent on the transcription factor retinoic acid receptor–related orphan receptor (RORα), which is also expressed in common ILC progenitors. To elucidate the developmental pathway...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Ghaedi, Maryam, Shen, Zi Yi, Orangi, Mona, Martinez-Gonzalez, Itziar, Wei, Lisa, Lu, Xiaoxiao, Das, Arundhoti, Heravi-Moussavi, Alireza, Marra, Marco A., Bhandoola, Avinash, Takei, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062532/
https://ncbi.nlm.nih.gov/pubmed/31816636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182293
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