The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

The actin cytoskeleton is a dynamic array of filaments that undergoes rapid remodeling to drive many cellular processes. An essential feature of filament remodeling is the spatio-temporal regulation of actin filament nucleation. One family of actin filament nucleators, the Diaphanous-related formins...

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Publicat a:J Biol Chem
Autors principals: Chen, Anan, Arora, Pam D., Lai, Christine C., Copeland, John W., Moraes, Trevor F., McCulloch, Christopher A., Lavoie, Brigitte D., Wilde, Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062178/
https://ncbi.nlm.nih.gov/pubmed/32005666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010476
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