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The noncanonical small heat shock protein HSP-17 from Caenorhabditis elegans is a selective protein aggregase

Small heat shock proteins (sHsps) are conserved, ubiquitous members of the proteostasis network. Canonically, they act as “holdases” and buffer unfolded or misfolded proteins against aggregation in an ATP-independent manner. Whereas bacteria and yeast each have only two sHsps in their genomes, this...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Iburg, Manuel, Puchkov, Dmytro, Rosas-Brugada, Irving U., Bergemann, Linda, Rieprecht, Ulrike, Kirstein, Janine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062175/
https://ncbi.nlm.nih.gov/pubmed/32001616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011185
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